Suppository
BiomeNourish™ Moisture + Comfort
This therapy is used for internal vaginal dryness, irritation, or tissue sensitivity, including microbiome recovery and hormone-free support for atrophy-related symptoms.
It may be used as a primary support for dryness, as part of recovery after treatment, or alongside other therapies when tissue comfort and hydration are needed.
This therapy may also be considered when internal or external vaginal dryness, irritation, or discomfort is contributing to intimacy-related discomfort or reduced sexual comfort.
What It Helps With:
Internal vaginal dryness or irritation
Reduced moisture or comfort inside the vagina
Tissue sensitivity or fragility
Comfort support during intimacy when dryness is a contributing factor
Recovery support after antimicrobial or other treatments
Hormone-free internal moisture support
Subscribe for refills and save
Shipped every 30 days or more$62.00
$69.00
One-Time Purchase
$69.00
A $20 consultation fee will be added at checkout. Your fee includes a virtual visit with a certified OB-GYN, intake review, and secure messaging for 12 months.
Your requested treatment may be adjusted if a different option is more appropriate. Learn More
Compounded
Non-hormonal
HSA/FSA eligible
Free delivery
Long-term microbiome support
Microbiome support protocols are recommended following your treatment to help maintain long-term vaginal microbiome health.
$101.00
pH-supportive microbiome recovery therapy to help support a low-pH, lactobacillus-friendly vaginal environment.
$62.00
Hormone-free moisture and tissue support for internal and external vaginal dryness, irritation, and comfort.
Inside the vagina
BiomeNourish™ Moisture + Comfort Suppository
Count: 15 suppositories
Active ingredients: Hyaluronic Acid (Sodium Hyaluronate) 5 mg; Vitamin E 4 mg
Inactive ingredients: BiomeNourish™ Suppository Base - Vaginal suppository base designed to melt at body temperature for localized delivery, with ceramides and a proprietary microbiome-supporting prebiotic.
This therapy is designed to support local hydration, barrier function, and tissue comfort.
Prescription grade hyaluronic acid is included to support hydration and water retention.
Vitamin E is included to support tissue comfort and barrier function.
This suppository may help support a tissue environment that is more stable and resilient, which can be an important part of vaginal microbiome recovery.
In many care pathways, this therapy is used alongside microbiome-directed treatments when both pH balance and tissue support are needed.
Because this option is hormone-free, it may also be considered for patients who prefer to avoid hormones or who may benefit from added internal moisture support alongside other clinician-directed therapies.
Some patients notice improved moisture and comfort with regular use. Response time can vary.
A mild increase in discharge can occur as the suppository melts.
Insert 1 suppository vaginally every other night at bedtime as needed for dryness, or as directed by your clinician.
- Hormone-free moisture-support product
- For vaginal use only
- Does not treat yeast, BV, or STI infections on its own
- Should be reviewed if new discharge, odor, bleeding, or worsening pain develops
- BiomeNourish™ Moisture + Comfort Suppository (This Option): hormone-free internal moisture and tissue support on an every-other-night cadence.
- BiomeNourish™ Moisture + Comfort Cream: hormone-free moisture and tissue support for internal and external dryness.
- BiomeNourish™ Lactic Acid Vaginal Suppository: microbiome-directed support used when low pH and lactobacillus support are part of the care plan.
- Estradiol or Estriol: local hormone options that may be considered when hormone therapy is appropriate.
- DHEA: a local hormone-based option that may be considered when clinician review suggests it is appropriate.
- Online intake
- Clinician review
- 15 custom compounded vaginal suppositories shipped discreetly
- HSA/FSA may be eligible
Suppository
BiomeNourish™ Moisture + Comfort
Subscribe for refills and save
Shipped every 30 days or more$62.00
$69.00
One-Time Purchase
$69.00
A $20 consultation fee will be added at checkout. Your fee includes a virtual visit with a certified OB-GYN, intake review, and secure messaging for 12 months.
Your requested treatment may be adjusted if a different option is more appropriate. Learn More
This therapy is used for internal vaginal dryness, irritation, or tissue sensitivity, including microbiome recovery and hormone-free support for atrophy-related symptoms.
It may be used as a primary support for dryness, as part of recovery after treatment, or alongside other therapies when tissue comfort and hydration are needed.
This therapy may also be considered when internal or external vaginal dryness, irritation, or discomfort is contributing to intimacy-related discomfort or reduced sexual comfort.
What It Helps With:
Internal vaginal dryness or irritation
Reduced moisture or comfort inside the vagina
Tissue sensitivity or fragility
Comfort support during intimacy when dryness is a contributing factor
Recovery support after antimicrobial or other treatments
Hormone-free internal moisture support
Compounded
Non-hormonal
HSA/FSA eligible
Free delivery
Long-term microbiome support
Microbiome support protocols are recommended following your treatment to help maintain long-term vaginal microbiome health.
$101.00
pH-supportive microbiome recovery therapy to help support a low-pH, lactobacillus-friendly vaginal environment.
$62.00
Hormone-free moisture and tissue support for internal and external vaginal dryness, irritation, and comfort.
Inside the vagina
BiomeNourish™ Moisture + Comfort Suppository
Count: 15 suppositories
Active ingredients: Hyaluronic Acid (Sodium Hyaluronate) 5 mg; Vitamin E 4 mg
Inactive ingredients: BiomeNourish™ Suppository Base - Vaginal suppository base designed to melt at body temperature for localized delivery, with ceramides and a proprietary microbiome-supporting prebiotic.
This therapy is designed to support local hydration, barrier function, and tissue comfort.
Prescription grade hyaluronic acid is included to support hydration and water retention.
Vitamin E is included to support tissue comfort and barrier function.
This suppository may help support a tissue environment that is more stable and resilient, which can be an important part of vaginal microbiome recovery.
In many care pathways, this therapy is used alongside microbiome-directed treatments when both pH balance and tissue support are needed.
Because this option is hormone-free, it may also be considered for patients who prefer to avoid hormones or who may benefit from added internal moisture support alongside other clinician-directed therapies.
Some patients notice improved moisture and comfort with regular use. Response time can vary.
A mild increase in discharge can occur as the suppository melts.
Insert 1 suppository vaginally every other night at bedtime as needed for dryness, or as directed by your clinician.
- Hormone-free moisture-support product
- For vaginal use only
- Does not treat yeast, BV, or STI infections on its own
- Should be reviewed if new discharge, odor, bleeding, or worsening pain develops
- BiomeNourish™ Moisture + Comfort Suppository (This Option): hormone-free internal moisture and tissue support on an every-other-night cadence.
- BiomeNourish™ Moisture + Comfort Cream: hormone-free moisture and tissue support for internal and external dryness.
- BiomeNourish™ Lactic Acid Vaginal Suppository: microbiome-directed support used when low pH and lactobacillus support are part of the care plan.
- Estradiol or Estriol: local hormone options that may be considered when hormone therapy is appropriate.
- DHEA: a local hormone-based option that may be considered when clinician review suggests it is appropriate.
- Online intake
- Clinician review
- 15 custom compounded vaginal suppositories shipped discreetly
- HSA/FSA may be eligible
The Base Designed for the Vaginal Ecosystem
BiomeNourish™ is a microbiome-supportive prescription base, available as a cream and suppository, designed specifically for vulvar and vaginal tissue. Using patented Bio-Match® Technology, it aligns with the natural vaginal environment to support comfort, healing, and long-term balance before, after, or alongside treatment.
Petroleum-derived ingredients like propylene glycol
Formulated for use on vulvar and vaginal tissue
Hyperosmolar
Iso-osmolar
Not pH matched
pH + osmolality matched
Your personalized treatment journey, step by step
Step 1
Select & Buy Your Care
Filter by your symptoms to choose and purchase your appropriate treatment
Step 2
Complete Your Intake
A licensed OB-GYN will review your health info and approve your selected treatment or recommend a more appropriate option
Step 3
Free Home Delivery
Your prescription is sent discreetly to your home with free two-day shipping so you can get care without the extra trip
After checkout, you’ll complete a brief medical intake about your symptoms and health history. A licensed provider will review your information, typically within 24 hours, to determine whether the requested treatment is appropriate for you. Throughout the process, you’ll have access to secure messaging through your patient dashboard, allowing you to communicate directly with your provider if additional information or follow-up is needed.
If approved, your prescription will be sent to a licensed compounding pharmacy and shipped directly to your door. If your provider determines that a different treatment may be more appropriate, they may recommend an alternative treatment plan based on your symptoms, health history, and clinical judgment.
Compounded medications are customized treatments prepared by a licensed compounding pharmacy under the direction of a healthcare provider. Unlike mass-produced medications, compounded therapies can be tailored to specific patient needs, including the ingredients used, strength, delivery method, or formulation base.
At Good Clean Clinical Care™, many prescriptions are formulated using our proprietary BiomeNourish™ base, which is designed to support vaginal and vulvar tissue comfort while helping maintain a healthy vaginal environment.
Our treatments use a specialized base, BiomeNourish™, developed with patented Bio-Match® technology to better align with the vaginal environment. This helps support beneficial bacteria while delivering treatment, improving comfort and promoting a healthier microbiome over time. Unlike many standard prescription treatments that use generic petroleum-based creams which can disrupt the natural pH and may irritate sensitive tissue, leading to discomfort or reduced tolerability, our formulations are designed specifically for vaginal and vulvar tissue.
Some medications are eligible for refills, while others may require a new provider review before additional treatment can be prescribed.
For eligible prescriptions, you may choose Auto-Refill for convenient ongoing treatment or request one-time refills directly from your patient dashboard when they become available. Refill eligibility and availability will be displayed on your Prescriptions page.
Prescription orders are typically reviewed by a provider within 24 hours. Once approved, prescriptions are prepared by our pharmacy partner and generally arrive within 3-5 business days.